Journal
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
Volume 38, Issue 1, Pages 3-19Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0167-8760(00)00127-6
Keywords
event-related potentials; P300; biomedical assay; clinical testing; coefficient of variation
Funding
- NIAAA NIH HHS [3P0 AA06420-16S1] Funding Source: Medline
- NIDA NIH HHS [R01-DA11737-02] Funding Source: Medline
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Use of the P300 event-related brain potential (ERP) as a clinical assay is reviewed and assessed by comparing its distribution qualities with normative biomedical testing data from published studies. The coefficient of variation statistic was calculated for P300 data and a variety of clinical testing data. P300 amplitude and latency variability was found to be highly comparable and sometimes superior to routinely employed biomedical assays. These results are discussed in terms of how to control inter-group ERP variability and the application of normative P300 data in clinical settings. (C) 2000 Elsevier Science B.V. All rights reserved.
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