Journal
HAUTARZT
Volume 51, Issue 10, Pages 738-745Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s001050051207
Keywords
high-dose steroid puls therapie; pharmacological basics; mechanisms of action; dermatological indications
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In recent years, high-dose steroid pulse therapy has been considered an effective treatment regimen in a number of non-dermatological diseases. This review addresses in the first part the pharmacological basics and mechanisms of action of high-dose glucocorticosteroid therapy. In the second part, we discuss the clinical experience using this treatment for dermatological diseases including pemphigus vulgaris, pyoderma gangrenosum,alopecia areata,and dermatomyositis.
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