Journal
JOURNAL OF NATURAL PRODUCTS
Volume 63, Issue 10, Pages 1434-1436Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np000149o
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Two novel acyclic diaza alkenynes, clathculins A and B (1 and 2), were isolated from the Indo-Pacific sponge Clathrina aff. reticulum collected in Sodwana Bay, South Africa. The structure of the mixture of the two unstable inseparable compounds was established by spectroscopic analysis, mainly 1D and 2D NMR measurements and two chemical transformations. Clathculins A and B are the first reported linear marine metabolites containing a 1,2-diaminoethane moiety.
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