4.4 Article

Genetic control of cell size

Journal

CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 10, Issue 5, Pages 529-535

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(00)00123-4

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Over the past 25 years, the genetic control of cell size has mainly been addressed in yeast, a single-celled organism. Recent insights from Drosophila have shed light on the signalling pathways responsible for adjusting and maintaining cell size in metazoans. Evidence is emerging for a signalling cascade conserved in evolution that links external nutrient sources to cell size.

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