Journal
JOURNAL OF CLINICAL GASTROENTEROLOGY
Volume 31, Issue 3, Pages 243-245Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00004836-200010000-00013
Keywords
thrombotic thrombocytopenic purpura; acute pancreatitis
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Thrombotic thrombocytopenic purpura (TTP) is a rare syndrome of unknown cause with an estimated incidence of one case per million. The disease is characterized by a pentad of symptoms: thrombocytopenia, microangiopathic hemolytic anemia, neurologic changes, renal dysfunction, and fever. It causes thrombosis in the microvasculature of several organs, producing diverse manifestations. Acute pancreatitis (AP) is a well-described consequence of TTP. We report a patient who developed TTP after presenting with AP, suggesting pancreatitis to be the cause, rather than a consequence, of TTP.
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