Journal
CLINICAL GENETICS
Volume 58, Issue 4, Pages 270-279Publisher
MUNKSGAARD INT PUBL LTD
DOI: 10.1034/j.1399-0004.2000.580404.x
Keywords
basement membranes; bone; cartilage; collagen; development; genes; mutations; procollagen
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Collagens are some of the major building blocks of the vertebrate body. In addition to their structural role, they are important for cell guidance during development and for maintaining tissue integrity. In their absence, phenotypes range from lethal to mild. These studies demonstrate that collaens, in their rich array, play important roles in development and are significant elements in reading the developmental code.
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