Journal
BIOINFORMATICS
Volume 30, Issue 17, Pages 2521-2523Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btu148
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Funding
- National Institutes of Health [R01 GM103551]
- Agilent Technologies
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A Summary: Skyline is a Windows client application for targeted proteomics method creation and quantitative data analysis. The Skyline document model contains extensive mass spectrometry data from targeted proteomics experiments performed using selected reaction monitoring, parallel reaction monitoring and data-independent and data-dependent acquisition methods. Researchers have developed software tools that perform statistical analysis of the experimental data contained within Skyline documents. The new external tools framework allows researchers to integrate their tools into Skyline without modifying the Skyline codebase. Installed tools provide point-and-click access to downstream statistical analysis of data processed in Skyline. The framework also specifies a uniform interface to format tools for installation into Skyline. Tool developers can now easily share their tools with proteomics researchers using Skyline.
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