Journal
BIOINFORMATICS
Volume 30, Issue 17, Pages 2524-2526Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btu305
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Funding
- NSF CAREER award [1054826]
- NSF SI2-SSE [1047962]
- [ETH-30 11-2]
- Direct For Biological Sciences
- Div Of Biological Infrastructure [1054826, 1501900] Funding Source: National Science Foundation
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A Summary: MSstats is an R package for statistical relative quantification of proteins and peptides in mass spectrometry-based proteomics. Version 2.0 of MSstats supports label-free and label-based experimental workflows and data-dependent, targeted and data-independent spectral acquisition. It takes as input identified and quantified spectral peaks, and outputs a list of differentially abundant peptides or proteins, or summaries of peptide or protein relative abundance. MSstats relies on a flexible family of linear mixed models.
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