4.7 Article

EVpedia: a community web portal for extracellular vesicles research

Journal

BIOINFORMATICS
Volume 31, Issue 6, Pages 933-939

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btu741

Keywords

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Funding

  1. National Research Foundation of Korea (NRF) grant - Korea government (MSIP) [2014-023004]
  2. Ministry of Health and Welfare grant - Korea government [A120273]
  3. KRIBB Research Initiative Program
  4. National Junior Research Fellowship [2014-048579]
  5. BK21 PLUS program - Ministry of Education, Science and Technology, Republic of Korea [10Z20130012243]
  6. ICREA Funding Source: Custom
  7. MRC [MR/J003360/1] Funding Source: UKRI
  8. Grants-in-Aid for Scientific Research [26290047, 26310106, 25112711, 221S0001] Funding Source: KAKEN
  9. Medical Research Council [MR/J003360/1] Funding Source: researchfish

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Motivation: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures and components, online searches for EV-related publications and vesicular components are currently challenging. Results: We present an improved version of EVpedia, a public database for EVs research. This community web portal contains a database of publications and vesicular components, identification of orthologous vesicular components, bioinformatic tools and a personalized function. EVpedia includes 6879 publications, 172 080 vesicular components from 263 high-throughput datasets, and has been accessed more than 65 000 times from more than 750 cities. In addition, about 350 members from 73 international research groups have participated in developing EVpedia. This free web-based database might serve as a useful resource to stimulate the emerging field of EV research.

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