4.7 Article

PSAR-Align: improving multiple sequence alignment using probabilistic sampling

Journal

BIOINFORMATICS
Volume 30, Issue 7, Pages 1010-1012

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btt636

Keywords

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Funding

  1. National Research Foundation of Korea [2012R1A1A1015186]
  2. National Institutes of Health [HG006464]
  3. National Research Foundation of Korea [2012R1A1A1015186] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  4. Div Of Biological Infrastructure
  5. Direct For Biological Sciences [1262575] Funding Source: National Science Foundation

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We developed PSAR-Align, a multiple sequence realignment tool that can refine a given multiple sequence alignment based on suboptimal alignments generated by probabilistic sampling. Our evaluation demonstrated that PSAR-Align is able to improve the results from various multiple sequence alignment tools.

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