4.7 Article

MetaboNetworks, an interactive Matlab-based toolbox for creating, customizing and exploring sub-networks from KEGG

Journal

BIOINFORMATICS
Volume 30, Issue 6, Pages 893-895

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btt612

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Funding

  1. Medical Research Council - Public Health England (MRC-PHE) Centre for Environment & Health PhD-studentship
  2. Medical Research Council National Institute for Health Research (MRC-NIHR) National Phenome Centre
  3. MRC [G0801056, MC_PC_12025] Funding Source: UKRI
  4. Medical Research Council [MC_PC_12025, G0801056] Funding Source: researchfish

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MetaboNetworks is a tool to create custom sub- networks in Matlab using main reaction pairs as defined by the Kyoto Encyclopaedia of Genes and Genomes and can be used to explore transgenomic interactions, for example mammalian and bacterial associations. It calculates the shortest path between a set of metabolites (e. g. biomarkers from a metabonomic study) and plots the connectivity between metabolites as links in a network graph. The resulting graph can be edited and explored interactively. Furthermore, nodes and edges in the graph are linked to the Kyoto Encyclopaedia of Genes and Genomes compound and reaction pair web pages.

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