Journal
NATURE STRUCTURAL BIOLOGY
Volume 7, Issue -, Pages 973-977Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/80754
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Structure-based biological discovery is entering a new era with the development of industrialized macromolecular structure determination pipelines. Intense, highly focused X-rays from integrated synchrotron radiation beam lines combined with significant advances in protein expression, purification, and micro-crystallization automation allow for the full streamlining of the traditionally tedious and time consuming process of determining the three dimensional structures of macromolecules.
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