Journal
BIOINFORMATICS
Volume 29, Issue 20, Pages 2641-2642Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btt454
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Funding
- U.S. Department of Energy, Office of Biological and Environmental Research (DOE-BER) Genome Science Program
- DOE [DE-AC06-76RL01830]
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At the rate that prokaryotic genomes can now be generated, comparative genomics studies require a flexible method for quickly and accurately predicting orthologs among the rapidly changing set of genomes available. SPOCS implements a graph-based ortholog prediction method to generate a simple tab-delimited table of orthologs and in addition, html files that provide a visualization of the predicted ortholog/paralog relationships to which gene/protein expression metadata may be overlaid.
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