Journal
PEDIATRICS
Volume 106, Issue 5, Pages 973-976Publisher
AMER ACAD PEDIATRICS
DOI: 10.1542/peds.106.5.973
Keywords
influenza; cost-effectiveness; vaccination; children; cost
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Objective. The economic impact of routine vaccination of preschool children with inactivated influenza vaccine was investigated. Design. A decision analysis was performed using data from the literature. Direct and indirect costs of each vaccination strategy were calculated and compared with a strategy of not vaccinating. Setting. Two settings were evaluated: a setting in which vaccination was available during flexible hours and a setting in which vaccination was available only during usual work hours (8:00 am-5:00 pm). Results. Vaccination resulted in a net cost savings in both settings. The net savings per vaccine recipient were $21.28 in the flexible setting and $1.20 in the restricted setting. Although the analysis was performed for the inactivated vaccine, sensitivity analysis showed that the nasal vaccine could also result in a net cost savings depending on the price of the cold-adapted vaccine when it is licensed. Conclusion. Vaccinating preschool children is economically advantageous. Serious consideration should be given to recommending vaccination in this age group.
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