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Different roles for androgens and estrogens in the susceptibility to autoimmune rheumatic diseases

Journal

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
Volume 26, Issue 4, Pages 825-+

Publisher

W B SAUNDERS CO
DOI: 10.1016/S0889-857X(05)70171-X

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Androgens and estrogens modulate susceptibility and progression to autoimmune rheumatic disease. At any concentration, androgens seem to be primarily suppressive on cellular and humoral immunity whereas at physiologic concentrations, estrogens seem to enhance humoral immunity and decrease cellular immunity.

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