4.7 Article

ANGES: reconstructing ANcestral GEnomeS maps

Journal

BIOINFORMATICS
Volume 28, Issue 18, Pages 2388-2390

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bts457

Keywords

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Funding

  1. Discovery Grant from the Natural Sciences and Engineering Research Council of Canada [249834-2011]
  2. Simon Fraser University Undergraduate Summer Research Award
  3. Simon Fraser University Graduate Fellowship
  4. Agence Nationale pour la Recherche grant [ANR-10-BINF-01-01 Ancestrome]

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ANGES is a suite of Python programs that allows reconstructing ancestral genome maps from the comparison of the organization of extant-related genomes. ANGES can reconstruct ancestral genome maps for multichromosomal linear genomes and unichromosomal circular genomes. It implements methods inspired from techniques developed to compute physical maps of extant genomes. Examples of cereal, amniote, yeast or bacteria ancestral genomes are provided, computed with ANGES.

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