Journal
BIOINFORMATICS
Volume 28, Issue 18, Pages 2391-2393Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bts446
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Funding
- Human Frontier Science Program [RGY0079/ 55 2009-C]
- Leverhulme Trust
- Medical Research Council [G0600084] Funding Source: researchfish
- MRC [G0600084] Funding Source: UKRI
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Motivation: To better analyze low-resolution cryo electron microscopy maps of macromolecular assemblies, component atomic structures frequently have to be flexibly fitted into them. Reaching an optimal fit and preventing the fitting process from getting trapped in local minima can be significantly improved by identifying appropriate rigid bodies (RBs) in the fitted component. Results: Here we present the RIBFIND server, a tool for identifying RBs in protein structures. The server identifies RBs in proteins by calculating spatial proximity between their secondary structural elements.
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