Journal
BIOINFORMATICS
Volume 29, Issue 3, Pages 389-390Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bts697
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Funding
- Medical Research Council, UK
- Wellcome Trust
- Cancer Research-UK
- MRC [G0800024] Funding Source: UKRI
- Cancer Research UK [13031] Funding Source: researchfish
- Medical Research Council [G0800024] Funding Source: researchfish
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A: A significant proportion of eukaryote genomes consist of transposable element (TE)-derived sequence. These elements are known to have the capacity to modulate gene function and genome evolution. We have developed RetroSeq for detecting non-reference TE insertions from Illumina paired-end whole-genome sequencing data. We evaluate RetroSeq on a human trio from the 1000 Genomes Project, showing that it produces highly accurate TE calls.
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