Journal
BIOINFORMATICS
Volume 29, Issue 1, Pages 132-134Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bts656
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Funding
- Sanofi-Aventis
- EMBL-EBI/Sanger ESPOD program
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Drug versus Disease (DvD) provides a pipeline, available through R or Cytoscape, for the comparison of drug and disease gene expression profiles from public microarray repositories. Negatively correlated profiles can be used to generate hypotheses of drug-repurposing, whereas positively correlated profiles may be used to infer side effects of drugs. DvD allows users to compare drug and disease signatures with dynamic access to databases Array Express, Gene Expression Omnibus and data from the Connectivity Map.
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