4.7 Article

ChimeraScan: a tool for identifying chimeric transcription in sequencing data

Journal

BIOINFORMATICS
Volume 27, Issue 20, Pages 2903-2904

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btr467

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Funding

  1. Department of Defense
  2. Prostate Cancer Foundation
  3. National Institutes of Health [K99 CA149182-01]
  4. National Institutes of Health, Department of Defense
  5. Early Detection Research Network

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Next generation sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data.

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