4.7 Article

StochKit2: software for discrete stochastic simulation of biochemical systems with events

Journal

BIOINFORMATICS
Volume 27, Issue 17, Pages 2457-2458

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btr401

Keywords

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Funding

  1. National Institute of Biomedical Imaging and Bioengineering [R01EB007511]
  2. Institute for Collaborative Biotechnologies from the US Army Research Office [DFR3A-8-447850-23002]
  3. DOE [DE-FG02-04ER25621]
  4. NSF [IGERT DG02-21715, DMS-1001012]
  5. National Science Foundation

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StochKit2 is the first major upgrade of the popular StochKit stochastic simulation software package. StochKit2 provides highly efficient implementations of several variants of Gillespie's stochastic simulation algorithm (SSA), and tau-leaping with automatic step size selection. StochKit2 features include automatic selection of the optimal SSA method based on model properties, event handling, and automatic parallelism on multicore architectures. The underlying structure of the code has been completely updated to provide a flexible framework for extending its functionality.

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