4.7 Article

ODORactor: a web server for deciphering olfactory coding

Journal

BIOINFORMATICS
Volume 27, Issue 16, Pages 2302-2303

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btr385

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Funding

  1. National Natural Science Foundation of China [21002062, 30970981]
  2. Shanghai PuJiang Program [10PJ406800, 09PJ1406900]

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ODORactor is an open access web server aimed at providing a platform for identifying odorant receptors (ORs) for small molecules and for browsing existing OR-ligand pairs. It enables the prediction of ORs from the molecular structures of arbitrary chemicals by integrating two individual functionalities: odorant verification and OR recognition. The prediction of the ORs for several odorants was experimentally validated in the study. In addition, ODORactor features a comprehensive repertoire of olfactory information that has been manually curated from literature. Therefore, ODORactor may provide an effective way to decipher olfactory coding and could be a useful server tool for both basic olfaction research in academia and for odorant discovery in industry.

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