4.7 Article

METAL: fast and efficient meta-analysis of genomewide association scans

Journal

BIOINFORMATICS
Volume 26, Issue 17, Pages 2190-2191

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq340

Keywords

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Funding

  1. National Human Genome Research Institute [HG0002651, HG0005214]
  2. National Institute of Mental Health [MH084698]
  3. National Heart, Lung and Blood Institute [K99HL094535]
  4. National Institute for Diabetes and Digestive and Kidney Diseases [DK078150-03]
  5. National Cancer Institute [CA082659-IISI]

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METAL provides a computationally efficient tool for meta-analysis of genome-wide association scans, which is a commonly used approach for improving power complex traits gene mapping studies. METAL provides a rich scripting interface and implements efficient memory management to allow analyses of very large data sets and to support a variety of input file formats.

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