4.7 Article

RefProtDom: a protein database with improved domain boundaries and homology relationships

Journal

BIOINFORMATICS
Volume 26, Issue 18, Pages 2361-2362

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq426

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Funding

  1. National Library of Medicine [LM04969]

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RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications.

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