Journal
BIOINFORMATICS
Volume 26, Issue 20, Pages 2624-2625Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq480
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Funding
- U.K. Biotechnology and Biological Sciences Research Council (BBSRC) [BB/F010362, BB/F010346]
- BBSRC [BB/G530417/1, BB/F010362/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/G530417/1, BB/F010362/1] Funding Source: researchfish
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The defined secondary structure of proteins method is often considered the gold standard for assignment of secondary structure from three-dimensional coordinates. However, there are alternative methods. '2Struc: The Secondary Structure Server' has been created as a single point of access for eight different secondary structure assignment methods. It has been designed to enable comparisons between methods for analyzing the secondary structure content for a single protein. It also includes a second functionality, 'Compare-the-Protein' to enable comparisons of the secondary structure features from any one method to be made within a collection of nuclear magnetic resonance models, or between the crystal structures of two different proteins.
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