Journal
NATURE CELL BIOLOGY
Volume 2, Issue 11, Pages E207-E209Publisher
MACMILLAN PUBLISHERS LTD
DOI: 10.1038/35041139
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A large and diverse number of diseases are now recognized as 'conformational diseases', caused by adoption of non-native protein conformations that lead to aggregation. The recent conference, 'Alpha(1)-antitrypsin deficiency and other conformational diseases', held in Airlie, Virginia, USA (27-30 June, 2000) focused on some of the common pathways by which cells protect themselves from toxicity associated with protein misfolding and aggregation.
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