Journal
BIOINFORMATICS
Volume 25, Issue 11, Pages 1472-1473Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btp181
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Funding
- Netherlands Proteomics Centre
- Netherlands Bioinformatics Centre
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Motivation: Mass spectrometric protein quantitation has emerged as a high-throughput tool to yield large amounts of data on peptide and protein abundances. Currently, differential abundance data can be calculated from peptide intensity ratios by several automated quantitation software packages available. There is, however, still a great need for additional processing to validate and re. ne the quantitation results. Here, we present a software tool, termed StatQuant, that offers a set of statistical tools to process, filter, compare and represent data from several quantitative proteomics software packages such as MSQuant. StatQuant offers the researcher post-processing methods to achieve improved confidence on the obtained protein ratios.
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