4.7 Article

Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis

Journal

BIOINFORMATICS
Volume 25, Issue 12, Pages 1564-1565

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btp253

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Funding

  1. National Institutes of Health [R01 113655, 121904]

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The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria-Delbruck fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency.

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