Journal
BIOINFORMATICS
Volume 24, Issue 23, Pages 2790-2791Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btn531
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We have developed a software that applies ascertainment bias on simulated DNA sequences and calculates F-ST on them, so they can be used to generate neutral distributions that are appropriate to test whether the genetic differentiation of a particular gene between populations is compatible with neutral evolution, or, on the contrary, suggests local adaptation by natural selection.
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