Journal
BIOINFORMATICS
Volume 24, Issue 22, Pages 2630-2631Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btn504
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Funding
- Trinity College, Cambridge UK
- UK Medical Research Council
- Laboratory of Molecular Biology, Cambridge, UK
- European Bioinformatics Institute
- Kevin Karplus's National Institutes of Health [R01 GM068570]
- Julian Gough's European Union
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Profile Comparer (PRC) is a stand-alone program for scoring and aligning profile hidden Markov models (HMMs) of protein families. PRC can read models produced by SAM and HMMER, two popular profile HMM packages, as well as PSI-BLAST checkpoint. profiles. This application note provides a brief description of the profile-profile algorithm used by PRC.
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