Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 25, Issue 11, Pages 544-548Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0968-0004(00)01681-9
Keywords
-
Categories
Funding
- NIDDK NIH HHS [DK46984] Funding Source: Medline
- NIGMS NIH HHS [GM60372] Funding Source: Medline
Ask authors/readers for more resources
The ubiquitin-proteasome system fulfills an essential function in eukaryotes by controlling the levels of crucial intracellular regulatory proteins. In this system, a specific type of polyubiquitin chain acts as the proximal signal for targeting substrates to 26S proteasomes for degradation. Recent results have revealed important determinants of polyubiquitin-chain recognition by proteasomes, helping to explain the biological rationale behind this novel signaling mechanism.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
