Journal
MICROBES AND INFECTION
Volume 2, Issue 13, Pages 1599-1607Publisher
EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S1286-4579(00)01316-2
Keywords
plaque; biofilm; adhesion; coadhesion; adhesins
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Funding
- NIDCR NIH HHS [DE12505, DE3180] Funding Source: Medline
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Dental plaque is a complex biofilm that accumulates on the hard tissues (teeth) in the oral cavity. Although over 500 bacterial species comprise plaque, colonization follows a regimented pattern with adhesion of initial colonizers to the enamel salivary pellicle followed by secondary colonization through interbacterial adhesion. A variety of adhesins and molecular interactions underlie these adhesive interactions and contribute to plaque development and ultimately to diseases such as caries and periodontal disease. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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