Journal
JOURNAL OF ETHNOPHARMACOLOGY
Volume 73, Issue 1-2, Pages 101-109Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0378-8741(00)00268-3
Keywords
Picrorhiza scrophulariiflora; immunomodulatory activity; anti-inflammatory activity
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Extracts of the rhizomes of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae) were investigated for their in vitro and in vivo immunomodulatory properties. Diethyl ether extracts showed potent inhibitory activity towards the classical pathway of the complement system, the respiratory burst of activated polymorphonuclear leukocytes, and mitogen-induced proliferation of T-lymphocytes. Furthermore, such extracts showed anti-inflammatory activity towards carrageenan-induced paw edema. No effects were observed in experimentally induced arthritis in mice. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
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