Journal
MICROBES AND INFECTION
Volume 2, Issue 14, Pages 1743-1756Publisher
EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S1286-4579(00)01329-0
Keywords
interferon; hepatitis C virus; protein kinase; PKR
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Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. It is the only therapy for hepatitis C virus (HCV) infection; however, many virus isolates are resistant. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral responses. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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