Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 1, Issue 2, Pages 110-119Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/35040061
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Funding
- NIAID NIH HHS [R37 AI036929] Funding Source: Medline
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Actin-based cell motility is a complex process involving a dynamic, self-organizing cellular system. Experimental problems initially limited our understanding of this type of motility, but the use of a model system derived from a bacterial pathogen has led to a breakthrough. Now, all the molecular components necessary for dynamic actin self-organization and motility have been identified, setting the stage for future mechanistic studies.
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