4.4 Article

An efficient synthesis of sulfobacin A (flavocristamide B), sulfobacin B, and flavocristamide A

Journal

TETRAHEDRON
Volume 56, Issue 46, Pages 9129-9142

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(00)00768-7

Keywords

sulfonolipids; asymmetric aldol reaction; 2-hydroxy-3-pinanone; oxidation

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Sulfobacin A (flavocristamide B, 1), sulfobacin B (2), and flavocristamide A (3), biologically active sulfonolipids, have been efficiently synthesized utilizing the asymmetric aldol reaction of the Schiff base 8 derived from glycine eater and (+)-2-hydroxy-3-pinanone (HyPN). (C) 2000 Elsevier Science Ltd. All rights reserved.

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