Journal
ORGANIC LETTERS
Volume 2, Issue 24, Pages 3833-3836Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol0002572
Keywords
-
Categories
Ask authors/readers for more resources
[GRAPHICS] A well-defined chiral Ru catalyst RuCl(N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine)(eta (6)-arene) effectively promotes asymmetric transfer hydrogenation of 1-aryl-1,2-propanedione with HCOOH/N(C2H5)(3), leading preferentially to optically active 1-aryl-2-hydroxy-1-propanone with up to 99% ee and 89% yield at 10 degreesC, The reaction at 40 degreesC gives anti 1-aryl-1,2-propanediol with up to 95% ee and 78% yield, This is a highly efficient procedure for the synthesis of optically active anti-diols.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available