Journal
BIOSCIENCE REPORTS
Volume 20, Issue 6, Pages 443-463Publisher
PORTLAND PRESS LTD
DOI: 10.1023/A:1010450702670
Keywords
phospholipase C; sphingomyelinase; membrane fusion; liposomes; model membranes; non-bilayer lipids; non-lamellar lipid phase
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In the past decade lipid vesicle fusion induced by either bacterial PC-preferring phospholipase C, phosphatidylinositol-specific phospholipase C, sphingomyelinase, or a combination of phospholipase C and sphingomyelinase has been demonstrated. In the present paper, the experimental evidence is reviewed, and discussed in terms of the underlying molecular mechanisms of fusion, and of the possible physiological relevance of these findings.
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