Journal
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
Volume 14, Issue 6, Pages 1307-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/S0889-8588(05)70188-X
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The German Multicenter Study Group for Adult Acute Lymphoblastic Leukemia (GMALL) has conducted 5 consecutive trials with more than 3000 patients since 1981. This article provides an overview on aims, treatment concepts, and results of these studies. It includes brief summaries on the development of prognostic models within the GMALL group and on approaches for prophylaxis of CNS relapse, and it summarizes specific treatment concepts for mature B-lineage acute lymphocytic leukemia.
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