Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 1, Issue 3, Pages 208-216Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/35043032
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Desmosomes are intercellular adhesive junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells, thereby forming a three-dimensional supracellular scaffolding that provides tissues with mechanical strength. But desmosomes have also recently been recognized as sensors that respond to environmental and cellular cues by modulating their assembly state and, possibly, their signalling functions.
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