Journal
BIOELECTROMAGNETICS
Volume 31, Issue 1, Pages 28-38Publisher
WILEY
DOI: 10.1002/bem.20523
Keywords
magnetic field effects; yeast gene expression; proteome; morphology; metabolism
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Funding
- INSA Toulouse (BQR, Bonus Qualite Recherche)
- Genopole Toulouse
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We report results of a study of the effects of strong static (up to 16 T for 8 h) and pulsed (up to 55 T single-shot and 4 x 20 T repeated shots) magnetic fields on Saccharomyces cerevisiae cultures in the exponential phase of growth. In contrast to previous reports restricted to only a limited number of cellular parameters, we have examined a wide variety of cellular processes: genome-scale gene expression, proteome profile, cell viability, morphology, and growth, metabolic and fermentation activity after magnetic field exposure. None of these cellular activities were impaired in response to static or pulsed magnetic field exposure. Our results confirm and extend previous reports on the absence of magnetic field effects on yeast and support the hypothesis that magnetic fields have no impact on the transcriptional machinery and on the integrity of unicellular biological systems. Bioelectromagnetics 31:28-38, 2010. (c) 2009 Wiley-Liss, Inc.
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