Journal
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
Volume 81, Issue 12, Pages 1582-1586Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/apmr.2000.9173
Keywords
body mass index; cortisol; leptin; obesity; spinal cord injuries; rehabilitation
Categories
Ask authors/readers for more resources
Objective: To investigate the relations among serum leptin, body mass index (BMI), and various hormone levels in men with spinal cord injury (SCI). Design: Cross-sectional. Setting: University hospital that is a tertiary referral center., Participants: Forty-seven men with traumatic neurologically complete SCI and 47 age- and BMI-matched male controls. Main Outcome Measures: Baseline levels of various hormones were measured in subjects with SCI. Serum leptin and cortisol levels and BMI were measured in both groups. Results: Serum leptin was significantly higher in the group with SCI than in the control group. A linear relation was found between serum leptin and BMI in both groups separately. A polynomial relation was found between serum leptin level and BMI in the group with SCI. A J phenomenon is noted at the lowest BMI. Serum cortisol correlated significantly with serum leptin level in the group with SCI. Conclusion: Sympathetic denervation, peripheral nerve palsy, recurrent infections, and possible central neurotransmitter alterations after SCI may contribute to the elevation of serum leptin level in men with SCI.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available