Journal
ACCOUNTS OF CHEMICAL RESEARCH
Volume 33, Issue 12, Pages 841-847Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ar000062u
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This Account summarizes techniques for carrying out microfabrication of structures with dimensions down to 10 mum in microchannels that are 0.02-2 mm wide. These methods are largely based on the exploitation of laminar flow at low Reynolds number (Re) to control the spatial delivery of reagents. These methods are illustrated by fabrication of fibers, microelectrode arrays, arrays of crystals, and patterns of proteins and cells.
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