Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 4, Issue 6, Pages 669-677Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1367-5931(00)00150-2
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The concept of allosteric regulation has already been exploited in the creation of artificial ribozymes and the activities of certain ribozymes can be controlled allosterically by specific effecters. Ribozymes with such properties are in the spotlight as biosensors. Such artificial allosterically regulated ribozymes have potential utility as nucleic-acid-based biosensors.
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