Journal
INTERNAL MEDICINE
Volume 39, Issue 12, Pages 1111-1114Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.39.1111
Keywords
toxoplasmosis; highly active antiretroviral therapy
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We studied a Japanese patient who developed parkinsonian symptoms over 3 months before the diagnosis of acquired immunodeficiency syndrome. Brain MRI showed multiple lesions with mass effect and ring enhancement in the basal ganglia and subcortical white matter suggesting Toxoplasma infection. Anti-Toxoplasma therapy and highly active antiretroviral therapy for 6 months allowed improvement of parkinsonism, brain MRI findings, and immune system.
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