Journal
BIOCONTROL SCIENCE
Volume 14, Issue 1, Pages 35-38Publisher
SOC ANTIBACTERIAL & ANTIFUNGAL AGENTS, JAPAN
DOI: 10.4265/bio.14.35
Keywords
Cytotoxicity; Geosmin; 2-Methylisoborneol; Cultured cells; Musty oder
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The cytotoxicity of musty odor-emitting substances, geosmin (GM) and 2-methylisoborneol, at a concentration of 10 ng/L - 300mg/L was investigated using cultured mammalian cells. These two compounds exhibited no cytotoxicity in either the colony-formation of human KB cells or WST-1 assays of human -, monkey -, and dog -derived cells. These results suggest that the maximum concentration (700 ng/L) of GM found in the water of Lake Shinji is not toxic.
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