Journal
MOLECULAR BRAIN RESEARCH
Volume 84, Issue 1-2, Pages 158-161Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0169-328X(00)00239-4
Keywords
dopamine receptor; D1 mRNA; D2 mRNA; neuronal cell line; Ntera-3 cell
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There is evidence that D1 and D2 dopamine receptors are co-expressed on some neurons. As a potential model of co-expression we examined Ntera-2 cells using RT-PCR, and showed that they express D2 but not D1 receptors. D2 dopamine receptor expression was confirmed by quinpirole inhibition of forskolin-stimulated cAMP formation. Absence of DI dopamine receptors was confirmed by the inability of dopamine or SKF 81297 to increase cAMP. (C) 2000 Elsevier Science B.V. All rights reserved.
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