Journal
LANCET
Volume 356, Issue 9246, Pages 1981-1982Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(00)03312-2
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The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immunohistochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35.6% of samples and was associated with poor disease-free and overall survival.
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