Journal
BIOCONJUGATE CHEMISTRY
Volume 22, Issue 12, Pages 2369-2376Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bc200086c
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [90817101, 20905022, 20775023, 20865006]
- 973 National Basic Research Program of China [2007CB310500]
Ask authors/readers for more resources
Identification and quantification of small organic molecules capable of binding to a protein of interest with reasonable affinity and specificity is a central problem. Via developing DNA-encoded recognizing probe, we validate a proof-of-principle for constructing of small target-to-DNA conversion that screens the small molecule-protein interaction. Successful identification of beta-indole acetic acid, abscisic acid, or 2,4-dichlorophenoxyacetic acid/corresponding antibody binding implies its fascinating potential for interrogating small molecule/protein interaction.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available