Journal
JOURNAL OF MOLECULAR BIOLOGY
Volume 304, Issue 5, Pages 687-698Publisher
ACADEMIC PRESS LTD
DOI: 10.1006/jmbi.2000.4309
Keywords
RNA polymerase; RNA polymerase II; open complex; elongation complex; transcription
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Funding
- NIGMS NIH HHS [GM53665, GM41376] Funding Source: Medline
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Bacterial RNA polymerase and eukaryotic RNA polymerase II exhibit striking structural similarities, including similarities in overall structure, relative positions of subunits, relative positions of functional determinants, and structures and folding topologies of subunits. These structural similarities are paralleled by similarities in mechanisms of interaction with DNA. (C) 2000 Academic Press.
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